Published: April 3, 2025
Joy Murrath, known as Joy Piccolo O’Connell, is the widow of NFL player Brian Piccolo and a lifelong cancer research advocate. She founded the Brian Piccolo Cancer Research Fund, turning personal tragedy into a legacy of hope and impact.
Quick Facts Table
Full Name | Joy Murrath (now Joy Piccolo O’Connell) |
---|---|
Known For | Widow of Brian Piccolo, Cancer Advocate |
Children | Five (Three with Brian Piccolo) |
Occupation | Philanthropist, Foundation President |
Foundation | Brian Piccolo Cancer Research Fund |
Active Since | 1970 |
Location | United States |
Who Is Joy Murrath?
Joy Murrath is best known as the wife of Brian Piccolo, a former Chicago Bears player whose courageous battle with cancer captivated the nation. Born and raised in the United States, Joy met Brian while he was attending Wake Forest University. Their love story unfolded off the field and quickly became one of football’s most enduring tales.
They married in 1964 and had three daughters: Lori, Traci, and Kristi. Joy’s life changed forever in 1970 when Brian passed away from embryonal cell carcinoma at just 26 years old.
Turning Tragedy Into Purpose
Founding the Brian Piccolo Cancer Research Fund
Following Brian’s death, Joy didn’t fade into the background. Instead, she founded the Brian Piccolo Cancer Research Fund, transforming grief into a mission that would span generations. Established in 1970, the fund supports groundbreaking cancer research, patient treatment programs, and awareness campaigns.
Fundraising Milestones
Under Joy’s leadership:
- Nearly $10 million has been raised since inception.
- Donations helped establish endowed chairs at top cancer institutions, including Memorial Sloan Kettering and Rush University Medical Center.
- The fund expanded its focus from testicular cancer to breast and lung cancer research, saving countless lives.
Joy Murrath’s Personal Journey

Remarriage and Private Life
In 1973, Joy remarried Rick O’Connell and had two more children. Despite rebuilding her personal life, she remained fiercely committed to the cause. Joy took on the name Joy Piccolo O’Connell and continued her work at the foundation, often supported by her daughters.
Continued Leadership and Advocacy
Joy has participated in:
- Public speaking engagements to raise awareness.
- Community fundraisers in partnership with institutions like the Chicago Bears and Gavers Community Cancer Foundation.
- Events to honor her late husband and support families affected by cancer.
Long-Term Partnerships & Public Impact
Chicago Bears and the Piccolo Legacy
The Chicago Bears organization has been instrumental in promoting the foundation. Each year, they present the Brian Piccolo Award to a rookie and veteran player who exemplify courage, loyalty, teamwork, and dedication—traits Brian embodied.
Gavers Community Cancer Foundation
The Gavers Foundation alone has donated over $1 million to the Piccolo Fund, focusing particularly on breast cancer research. This enduring partnership exemplifies the fund’s national relevance and Joy’s networking impact.
The Enduring Message of “Brian’s Song”
In 1971, Brian Piccolo’s story was immortalized in the film Brian’s Song, which spotlighted his friendship with teammate Gale Sayers and his battle with cancer. The movie continues to draw new generations into Brian’s and Joy’s powerful narrative.
Frequently Asked Questions
Is Joy Piccolo still alive?
Yes, Joy Piccolo O’Connell is alive as of 2025. She continues her philanthropic work through the Brian Piccolo Cancer Research Fund and remains active in supporting cancer awareness efforts.
Did Joy Murrath remarry?
Yes, Joy Murrath remarried in 1973 to Rick O’Connell. Despite her new chapter, she retained her commitment to Brian Piccolo’s legacy and remains active under the name Joy Piccolo O’Connell.
What is the Brian Piccolo Cancer Research Fund?
It’s a nonprofit organization founded in 1970 by Joy Murrath to fund cancer research. It initially focused on testicular cancer and later expanded to breast and lung cancers.
Joy and Brian Piccolo’s children?
Joy and Brian Piccolo had three daughters: Lori, Traci, and Kristi.
What has Joy Piccolo accomplished?
Joy has led the Brian Piccolo Cancer Research Fund for over 50 years, raising millions for cancer research, forming national partnerships, and advocating for better patient care and treatment.
Conclusion
Joy Murrath’s story is a profound example of transforming personal tragedy into meaningful legacy. Through the Brian Piccolo Cancer Research Fund, she has impacted thousands of lives, funded vital research, and ensured her husband’s memory lives on. Her quiet strength, unwavering mission, and lifelong advocacy continue to inspire both the sports and medical communities.